Molecular Biology of Drug ...

Molecular Biology of Drug Addiction, Leki

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Molecular Biology
Edited by
Rafael Maldonado
Humana Press
of Drug Addiction
Molecular Biology of Drug Addiction
Molecular Biology
of Drug Addiction
Edited by
Rafael Maldonado
Laboratory of Neuropharmacology
Health and Life Sciences School
Universitat Pompeu Fabra
Barcelona, Spain
Humana Press
Totowa, New Jersey
 © 2003 Humana Press Inc.
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All rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or
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The content and opinions expressed in this book are the sole work of the authors and editors, who have warranted due
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or omissions or for any consequences arising from the information or opinions presented in this book and make no
warranty, express or implied, with respect to its contents.
Due diligence has been taken by the publishers, editors, and authors of this book to assure the accuracy of the information
published and to describe generally accepted practices. The contributors herein have carefully checked to ensure that
the drug selections and dosages set forth in this text are accurate and in accord with the standards accepted at the time
of publication. Notwithstanding, since new research, changes in government regulations, and knowledge from clinical
experience relating to drug therapy and drug reactions constantly occur, the reader is advised to check the product
information provided by the manufacturer of each drug for any change in dosages or for additional warnings and
contraindications. This is of utmost importance when the recommended drug herein is a new or infrequently used drug.
It is the responsibility of the treating physician to determine dosages and treatment strategies for individual patients.
Further, it is the responsibility of the health care provider to ascertain the Food and Drug Administration status of each
drug or device used in their clinical practice. The publishers, editors, and authors are not responsible for errors or
omissions or for any consequences from the application of the information presented in this book and make no warranty,
express or implied, with respect to the contents in this publication.
This publication is printed on acid-free paper.
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Cover design by Patricia F. Cleary.
Cover illustration: Disruption of the CREB gene in brain by Cre/loxP-mediated recombination (Chapter 2, Fig. 5).
See
complete illustration on p. 33 and discussion on p. 30.
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Printed in the United States of America. 10 9 8 7 6 5 4 3 2 1
Library of Congress Cataloging-in-Publication Data
Molecular biology of drug addiction / edited by Rafael Maldonado
p. cm.
Includes bibliographical references and index.
ISBN 1-58829-060-3 (alk. paper)
1. Drug abuse--Molecular aspects. I. Maldonado, Rafael.
RC564 .M638 2003
616.86--dc21
2002024057
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